When it comes to publishing research and study findings, the vast majority of publications require a study that has a singular, set protocol that is applied in the same manner to all the patients in that study — i.e. a double-blind, placebo-controlled. However, when each patient receives an entirely unique form of therapy — as is the case with the Tolerance Induction Program (TIP) — each patient is essentially their own control. This approach, which is one of the foundations of the success of TIP, does not fit the standard model for research publications. Medical journals rarely explore how mixed model statistical analytics and vector modeling can be applied to patient care.
Despite the complex nature of our treatment protocol and the traditional parameters for research publication, Dr. Randhawa and his research team have authored and submitted publications describing the data from the Tolerance Induction Program via mixed model statistical analysis. Dr. Randhawa has also presented multiple times at the AAAAI and the ACAAI meetings over the last five years.
Dr. Randhawa most recent peer reviewed journal can be found in the link below. Titled “Food anaphylaxis diagnostic marker compilation in machine learning design and validation” co-authored with data scientists Kirill Groshenkov and Grigori Sigalov, is the first peer-reviewed study to analyze the role and effectiveness of machine learning in actively treating patients with severe food allergies.:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0283141
Since 2005 Dr. Randhawa has directly presented or participated in the authorship of over 100 academic conferences, peer reviewed publications and educational lectures. Dr. Randhawa has maintained academic professorship at UCLA and UC Irvine. Building the Tolerance Induction Program requires expertise in molecular research, applied mathematics, clinical therapeutics and machine learning. All of these aspects have been shared over time at medical presentations and medical conferences. Unfortunately, typical “medical community” education only involves the clinical therapeutics side. It does not involve all aspects of how TIP was developed.
This is a short list of our work published in the space of food allergy including publications of the Tolerance Induction Program:
- Demographic, Clinical and Diagnostic Correlation of Almond Allergy in a Cohort of Nut Allergy Patients by Marsteller, N.L., Morphew, T., Randhawa, I., Ann. Allergy (2020).
- Evaluating the potential allergenicity of dietary proteins using model strong to non-allergenic proteins in germ-free mice….by Marsteller, N.L. et al. Food Chem Toxicol, 111398 (2020).
- Tolerance Induction Program Effect Explains Variation in Wheal Size, sIgE, and IgG4 in Peanut Allergic Children….by Randhawa, I., Marsteller, N.L., Morphew, T. J Allergy Ther 10:2 (2019)
- Allergy Evaluation During Hospitalized Asthma Improves Disease Management Outcomes by Brock, J.P., Nussbaum, E., Morphew, T.L., Marsteller, N.L. et al. SN Comprehensive Clinical Medicine. 1, 328-333 (2019).
- Correlation of negative skin-prick test results for tree nuts and successful tree nut challenges among children with peanut allergy….by Randhawa, I., Morphew, T. & Marsteller, N.L. Allergy and asthma proceedings : The Official Journal of Regional and State Allergy Societies. 39, 456-460 (2018).
- Experimental evaluation of the importance of colonization history in early-life gut microbiota assembly…. by Martinez, I., & Marsteller, N.L et al. Elife 7 (2018).
Learn more about our research here.