Data Dashboards

Publications

Tolerance Induction Program® Videos

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Webinars & Grand Rounds

 
 
 

CME Courses

Provider Guides

Provider Testimonials

Providers FAQs

Clinical questions about protocols, patient selection, and treatment management.

  • What are the main clinical differences between TIP and OIT?

    TIP offers a safer, more advanced, and personalized path to food freedom compared to OIT’s desensitization-based approach.

    Safety – TIP is designed to be safer, minimizing reaction risk through a data-driven, personalized approach, whereas OIT carries a higher risk of allergic reactions due to direct allergen exposure.
    Treatment Goal – TIP aims for true remission, allowing patients to eat freely without ongoing maintenance, while OIT focuses on desensitization, requiring lifelong daily dosing to maintain tolerance.

    Personalization – TIP uses AI-driven immune profiling to customize treatment for each patient based on biomarkers, whereas OIT follows a standardized protocol for individual allergens.

    Multi-Allergen Treatment – TIP treats multiple food allergies simultaneously, while OIT typically targets one allergen at a time.

    Diagnostic Testing & Monitoring – TIP relies on advanced diagnostics (IgE, IgG4, skin prick, basophil activation tests) to track immune shifts, while OIT has limited ongoing immune monitoring.

    Dosing & Lifestyle Impact – TIP eliminates lifelong dosing and rest periods, allowing a more flexible lifestyle, whereas OIT requires strict daily dosing and and activity restrictions.

  • What type of patient is a good candidate for TIP?

    TIP is for patients with IgE-mediated food allergies, regardless of severity or preexisting conditions.

    Ideal candidates include children and adults with multiple food allergies or a history of severe reactions, seeking a long-term solution beyond avoidance.

  • How is the Tolerance Induction Program informed by clinical research, and what is the function of your dedicated research division?

    Aperture Immunodiagnostics, our research branch and parent company, operates as a cutting-edge medical research institute focused on advancing treatments for food allergies and rare orphan disease. It conducts clinical research, develops diagnostic tools, and through the Baric Data Loop, generates the data that powers TIP’s precision-based approach. By continuously analyzing patient outcomes and refining treatment protocols, Aperture Immunodiagnostics helps improve safety, efficacy, and long-term success for food allergy patients.

    Learn more about the B.A.R.I.C Data Loop 

  • How is TIP regulated? Under what regulatory agencies?

    TIP, along with our diagnostic lab, research facility, and biobank, follows regulated standards set by the FDA and is overseen by our Institutional Review Board (IRB) Advarra, ensuring the highest levels of safety and compliance. We are also accredited and regulated by CAP (College of American Pathologists), CLIA (Clinical Laboratory Improvement Amendments), the California Department of Public Health, the U.S. Department of Health and Human Services, and the Medical Board of California. Additionally, our food lab's gummy doses are sent to a third party to verify the accurate protein dosage in each gummy.